BDBM285583 US10077269, Example 56::US10669279, Example 56::US9598421, Example 56::azetidin-1-yl[3-(4-chloro-2-methylphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=KDPKDOHAJHCGSZ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285583   

LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  22.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  43.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  84.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  3.93E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  22.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  3.93E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  84.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  3.93E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  22.7nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  43.1nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  84.5nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285583(US10077269, Example 56 | US10669279, Example 56 | ...)
Affinity DataIC50:  43.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent