BDBM285597 3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyclopro-pyl]imidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 70::US10669279, Example 70::US9598421, Example 70

SMILES Cc1cc(Cl)ccc1-c1c(nc2cccnn12)C(=O)N[C@@H]1C[C@@H]1F

InChI Key InChIKey=XIVVDTJZCTVMFP-QWHCGFSZSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285597   

LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  36.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  31nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  90nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  5.76E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  36.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  5.76E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  5.76E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  36.4nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  31nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  90nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285597(3-(4-chloro-2-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent