BDBM28564 2-[(2-{[4-(4-fluorophenyl)-12-methyl-5-thia-3,7,10,12-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3,7,10-pentaen-8-yl]amino}ethyl)amino]ethan-1-ol::thiazole-based tricyclic inhibitor, 32e

SMILES Cn1cnc2c(NCCNCCO)nc3sc(nc3c12)-c1ccc(F)cc1

InChI Key InChIKey=KMSKRTSNTUEYNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28564   

LigandPNGBDBM28564(2-[(2-{[4-(4-fluorophenyl)-12-methyl-5-thia-3,7,10...)
Affinity DataIC50:  8.60E+3nMT: 25°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM28564(2-[(2-{[4-(4-fluorophenyl)-12-methyl-5-thia-3,7,10...)
Affinity DataIC50:  75nMpH: 7.5 T: 22°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed