BDBM286219 7-methyl-2-(6-methylpyridin-3- yl)-3-methylimidazo[1,2- a]pyridine::US9518055, Example 16

SMILES Cc1c(nc2cc(C)ccn12)-c1cnccc1C

InChI Key InChIKey=MURZJPCIAYYNPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286219   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286219(7-methyl-2-(6-methylpyridin-3- yl)-3-methylimidazo...)
Affinity DataIC50:  68nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286219(7-methyl-2-(6-methylpyridin-3- yl)-3-methylimidazo...)
Affinity DataIC50:  204nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent