BDBM286237 2-(5-(3-cyclopropyl-6- fluoroimidazo[1,2-a]pyridin-2- yl)pyridin-3-yl)-1,1,1- trifluoropropan-2-ol::US9518055, Example 38

SMILES CC(O)(c1cncc(c1)-c1nc2ccc(F)cn2c1C1CC1)C(F)(F)F

InChI Key InChIKey=OWGUKRPUVVBJPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286237   

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286237(2-(5-(3-cyclopropyl-6- fluoroimidazo[1,2-a]pyridin...)
Affinity DataIC50:  1.12E+3nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286237(2-(5-(3-cyclopropyl-6- fluoroimidazo[1,2-a]pyridin...)
Affinity DataIC50:  6.30nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent