BDBM286344 US11220518, Ex. No. K2::US11780853, Example K2::US9518060, Example K2

SMILES CCOc1ccc(F)c(Nc2n[nH]c3c2CN(C(=O)N2C[C@@H](C)N(CC)C[C@@H]2C)C3(C)C)n1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286344   

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

US Patent
LigandPNGBDBM286344(US11220518, Ex. No. K2 | US11780853, Example K2 | ...)
Affinity DataKi:  2.11nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProtein kinase C beta type Isoform 2(Human)
Pfizer

US Patent
LigandPNGBDBM286344(US11220518, Ex. No. K2 | US11780853, Example K2 | ...)
Affinity DataKi:  2.11nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM286344(US11220518, Ex. No. K2 | US11780853, Example K2 | ...)
Affinity DataKi:  2.11nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent