BDBM286348 US11220518, Ex. No. K6::US11780853, Example K6::US9518060, Example K6

SMILES COCCCN1C[C@H](C)N(C[C@H]1C)C(=O)N1Cc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c2C1(C)C

InChI Key InChIKey=HPQAVQJTTFEWSN-CABCVRRESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286348   

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProtein kinase C beta type Isoform 2(Human)
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent