BDBM28638 cid_4076092::ethyl 2-({2-[(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate::isoquinolinone scaffold, 2

SMILES CCOC(=O)C(C)Oc1cccc2c1ccn(CC(=O)Nc1ccc3OCCOc3c1)c2=O

InChI Key InChIKey=KWMBIIQCLUIHDI-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 28638   

TargetSteroidogenic factor 1(Homo sapiens (Human))
Scripps Florida

LigandPNGBDBM28638(cid_4076092 | ethyl 2-({2-[(2,3-dihydro-1,4-benzod...)
Affinity DataEC50:  760nMAssay Description:The assay was to monitor the SF-1 activation state via co-transfection of CHO-K1 cells with a plasmid encoding a Gal4-SF-1 chimerical transcription f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroidogenic factor 1(Homo sapiens (Human))
Scripps Florida

LigandPNGBDBM28638(cid_4076092 | ethyl 2-({2-[(2,3-dihydro-1,4-benzod...)
Affinity DataIC50:  837nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
Scripps Florida

LigandPNGBDBM28638(cid_4076092 | ethyl 2-({2-[(2,3-dihydro-1,4-benzod...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Gal4-fused human SF1 LBD (198 to 462 residues) expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM28638(cid_4076092 | ethyl 2-({2-[(2,3-dihydro-1,4-benzod...)
Affinity DataIC50: >3.30E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEstrogen receptor(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM28638(cid_4076092 | ethyl 2-({2-[(2,3-dihydro-1,4-benzod...)
Affinity DataEC50:  1.26E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay