BDBM286394 US9518064, Example 6
SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3ccoc3)cc(OC)cc2o1
InChI Key InChIKey=QWYGESWGTOIWDM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 286394
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at full length human PAR4 expressed in HEK293 cells assessed as reduction in H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-Lys-Asn-Gly-NH2 i...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Early Development
Curated by ChEMBL
Affinity DataIC50: 1.86nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair