BDBM286473 2-Methoxy-6-(6-methoxy-4-((3-(tetrahydro-2H-pyran-4-yl)benzyl)oxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole::US9518064, Example 92

SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)C3CCOCC3)cc(OC)cc2o1

InChI Key InChIKey=IFQHAIFOVJMOBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286473   

TargetProteinase-activated receptor 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM286473(2-Methoxy-6-(6-methoxy-4-((3-(tetrahydro-2H-pyran-...)
Affinity DataIC50: 0.720nMT: 2°CAssay Description:The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent