BDBM28710 2-[4-({[2-(4-tert-butylphenyl)-4-methyl-1,3-thiazol-5-yl]formamido}methyl)phenoxy]-2-methylpropanoic acid::2-methyl-2-phenoxypropanoic acid, 25b::CHEMBL221074

SMILES Cc1nc(sc1C(=O)NCc1ccc(OC(C)(C)C(O)=O)cc1)-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=LUDKSNOGWAPFQY-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28710   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human PPARalpha receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  5nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  860nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50: >1.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
LigandPNGBDBM28710(CHEMBL221074 | 2-[4-({[2-(4-tert-butylphenyl)-4-me...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed