BDBM287151 US9567339, Example A.1.2

SMILES C=CC(=O)Nc1cccc(-c2ccc(C(N)=O)c3[nH]c(-c4ccnn4C4CCCCO4)cc23)c1C

InChI Key InChIKey=ZXZGHIWUVGGGQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287151   

TargetTyrosine-protein kinase BTK [393-659](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 287151BDBM287151(US9567339, Example A.1.2)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent