BDBM287205 US9567339, Example A.4.1

SMILES C=CC(=O)NCc1cccc(-c2ccc(C(N)=O)c3[nH]c(C4=CCN(S(C)(=O)=O)CC4)cc23)c1

InChI Key InChIKey=YROFMPHUAZCMHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287205   

TargetTyrosine-protein kinase BTK [393-659](Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 287205BDBM287205(US9567339, Example A.4.1)
Affinity DataIC50: 100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent