BDBM287979 (1R,2S)-2-(((2-(4- (dimethylamino)phenyl)quinazolin-4- yl)amino)methyl)-N,N-diethyl-1- phenylcyclopropanecarboxamide::US10087148, Example 46

SMILES CCN(CC)C(=O)[C@@]1(C[C@@H]1CNc1nc(nc2ccccc12)-c1ccc(cc1)N(C)C)c1ccccc1

InChI Key InChIKey=SYLCGUYZNULMNT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287979   

TargetSodium-dependent dopamine transporter(Human)
The United States of America As Represented By The Secretary, Department of Health and Human Services Office of Technology Transfer, National Institute of Health

US Patent
LigandPNGBDBM287979((1R,2S)-2-(((2-(4- (dimethylamino)phenyl)quinazoli...)
Affinity DataEC50:  243nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent