BDBM288119 Production of 7′-(3-chloro-2-fluorobenzylcarbamoyl)-cis-3-(methoxymethyl)-2′-methyl-1′,8′-dioxo-1′,2′,3′,8′-tetrahydrospiro[cyclobutane-1,4′-pyrido[1,2-a]pyrazin]-9′-yl acetate::US10087178, Example 37

SMILES COC[C@H]1C[C@@]2(C1)CN(C)C(=O)c1c(OC(C)=O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=GMRQOSIMRGUAMF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288119   

TargetProtein Nef(HIV-1)
Japan Tobacco

US Patent
LigandPNGBDBM288119(Production of 7′-(3-chloro-2-fluorobenzylcar...)
Affinity DataEC50:  0.700nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent