BDBM288255 7-Chloro-5-(2-isopropyl-6-(trifluoromethyl)pyrazolo[1,5-a]pyridin-7-::US10087185, Example 73

SMILES CC(C)c1cc2ccc(c(-c3cc(Cl)c4[nH]ncc4c3)n2n1)C(F)(F)F

InChI Key InChIKey=ONCMLRPNKIQCQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288255   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288255(7-Chloro-5-(2-isopropyl-6-(trifluoromethyl)pyrazol...)
Affinity DataIC50:  0.0100nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent