BDBM288386 US10087187, Compound 81

SMILES CCC(C)C(N)C(=O)OCc1nc2c(N)cc(nn2c1Nc1cccc(c1C)C(F)(F)F)N1CCOCC1

InChI Key InChIKey=CQFQJYXNXFQWDM-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 288386   

LigandPNGBDBM288386(US10087187, Compound 81)
Affinity DataKd:  2.69E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM288386(US10087187, Compound 81)
Affinity DataKd:  5nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288386(US10087187, Compound 81)
Affinity DataKd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM288386(US10087187, Compound 81)
Affinity DataKd: >3.02E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM288386(US10087187, Compound 81)
Affinity DataKd:  724nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent