BDBM288398 US10087187, Compound 97

SMILES Cc1c(F)cccc1Cc1c(CNCCO)nc2c(N)cc(nn12)N1CCOCC1

InChI Key InChIKey=YXMPDRZNZAKWOH-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 288398   

LigandPNGBDBM288398(US10087187, Compound 97)
Affinity DataKd:  1.60nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandPNGBDBM288398(US10087187, Compound 97)
Affinity DataKd:  200nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288398(US10087187, Compound 97)
Affinity DataKd:  912nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandPNGBDBM288398(US10087187, Compound 97)
Affinity DataKd:  3.72E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent

LigandPNGBDBM288398(US10087187, Compound 97)
Affinity DataKd:  1.12E+4nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan technology performed by DiscoveRx Corporation, Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
US Patent