BDBM288436 (E)-3-(3,5-difluoro-4-((5S,7R/5R,7S)-6-(2-fluoro-2-methylpropyl)-7-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)phenyl)acrylic acid::US10087191, Example 1
SMILES CC1Cc2cc3OCOc3cc2C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F
InChI Key InChIKey=DTLYVZWLSCXRPR-SNAWJCMRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288436
Affinity DataIC50: 0.770nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair