BDBM288635 (E)-3-(4-((1S,3R/1R,3S)-6-(1-ethyl-1H-pyrazol-4-yl)-5-fluoro-2-(2-fluoro-2-methylpropyl)-3-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-3,5-difluorophenyl)acrylic acid::US10087191, Example 47
SMILES CCn1cc(cn1)-c1ccc2C(N(CC(C)(C)F)C(C)Cc2c1F)c1c(F)cc(\C=C\C(O)=O)cc1F
InChI Key InChIKey=KTXBYWXZQOIPMY-RMKNXTFCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288635
Affinity DataIC50: 1.5nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair