BDBM289430 5-(1-isopropyl-5-(3-morpholinobicyclo[1.1.1]pentan-1-yl)-1H-pyrazol-3-yl)-3-(trifluoromethyl)pyridin-2-amine::US10093664, Example 11

SMILES CC(C)n1nc(cc1C12CC(C1)(C2)N1CCOCC1)-c1cnc(N)c(c1)C(F)(F)F

InChI Key InChIKey=UPFKDTKEPXQLAY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289430   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM289430(5-(1-isopropyl-5-(3-morpholinobicyclo[1.1.1]pentan...)
Affinity DataKd:  15nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent