BDBM290122 (4R)-4-amino-5-[(4-{[(7-methoxy-2-oxo-8-propyl-2H-chromen-3-yl)carbonyl]amino}-3-methylphenyl)amino]-5-oxopentanoicacid::US9572792, Compound 62

SMILES CCCc1c(OC)ccc2cc(C(=O)Nc3ccc(NC(=O)[C@H](N)CCC(O)=O)cc3C)c(=O)oc12

InChI Key InChIKey=RUDTYSGXBOPGQW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290122   

TargetSphingosine 1-phosphate receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM290122(US9572792, Compound 62 | (4R)-4-amino-5-[(4-{[(7-m...)
Affinity DataEC50:  3.10nMpH: 7.4Assay Description:The S1P1 activity of the compounds according to the invention, were tested using the GTP γ35S binding assay. The compounds were assessed for the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent