BDBM290149 US9573958, Compound 33

SMILES C[C@H](NCc1ccc2n(CC3CCCN3[C](=C)=O)c(NC(=O)c3ccc(Cl)cc3)nc2c1)C(C)(C)C

InChI Key InChIKey=BEDWKJCGDZYRIO-HSTJUUNISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290149   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290149(US9573958, Compound 33)
Affinity DataIC50:  7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent