BDBM290183 US9573958, Compound 12

SMILES C=CC(=O)N1CCC(n2c(=NC(=O)c3ccc(Cl)cc3)[nH]c3cc(CN[C@@H](C)C(C)(C)C)ccc32)CC1

InChI Key InChIKey=DWKZKXRZFPIRSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290183   

TargetTyrosine-protein kinase ITK/TSK(Human)
Principia Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 290183BDBM290183(US9573958, Compound 12)
Affinity DataIC50: 120nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
US Patent