BDBM290222 US9573958, Compound 20

SMILES C=CC(=O)N1CCCC(C1)n1c2ccccc2[nH]c1=NC(=O)c1ccc(s1)-c1cn[nH]c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290222   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290222(US9573958, Compound 20)
Affinity DataIC50:  0.600nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent