BDBM290269 10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-2(1H)-one hydrochloride::US10098883, Example 10::US10098883, Example 60::US10668071, Example 60

SMILES Brc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1

InChI Key InChIKey=BKPYMMXDHTZIRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290269   

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290269(10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...)
Affinity DataIC50:  34nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290269(10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...)
Affinity DataIC50:  14nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290269(10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...)
Affinity DataIC50:  34nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290269(10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...)
Affinity DataIC50:  14nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent