BDBM290308 (−)-trans-4-(2-Methylpiperidin-4-yl)-10-phenylpyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one hydrochloride::US10098883, Example 51::US10668071, Example 51

SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(ccnc3nn12)-c1ccccc1

InChI Key InChIKey=QUPXOQCUSLWZBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290308   

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290308(US10098883, Example 51 | (−)-trans-4-(2-Meth...)
Affinity DataIC50: 15nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290308(US10098883, Example 51 | (−)-trans-4-(2-Meth...)
Affinity DataIC50: 15nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent