BDBM290324 4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]pyrimido[1,2-b]indazol-2(1H)-one hydrochloride::US10098883, Example 67::US10668071, Example 67

SMILES FC(F)(F)c1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1

InChI Key InChIKey=HRTZQFUZXIJCKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290324   

TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290324(4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]p...)
Affinity DataIC50:  13nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPlasminogen [101-181](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290324(4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]p...)
Affinity DataIC50:  13nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent