BDBM290396 (3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyridin-3- yl)pyrrolidine-3-carboxylic acid::US10098902, Example 32::US10603330, Example 32::US11389464, Example 32

SMILES Cc1ccncc1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O

InChI Key InChIKey=WEMSXLMGPMXRPD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290396   

TargetArginase-2, mitochondrial(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetArginase-1(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetArginase-1(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetArginase-2, mitochondrial(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetArginase-2, mitochondrial(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetArginase-1(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290396BDBM290396((3R,4S)-3-amino-4-(3-boronopropyl)-1-(4-methylpyri...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent