BDBM290425 (1S,2S,4S)-1,4-diamino-2-(3-boronopropyl)cyclopentanecarboxylic acid::US10098902, Example 61

SMILES CC(OO)[C@]1(N)C[C@@H](N)C[C@@H]1CCCB(O)O

InChI Key InChIKey=QUAYJHOQACJAOT-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290425   

TargetArginase-1(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290425BDBM290425((1S,2S,4S)-1,4-diamino-2-(3-boronopropyl)cyclopent...)
Affinity DataIC50: 625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetArginase-2, mitochondrial(Human)
Mars

US Patent
LigandChemical structure of BindingDB Monomer ID 290425BDBM290425((1S,2S,4S)-1,4-diamino-2-(3-boronopropyl)cyclopent...)
Affinity DataIC50: 625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent