BDBM29074 ether-based lactam, 19c

SMILES FC(F)(F)CN1CCOc2c(nn(c2-c2ccc(Cl)cc2)-c2ccccc2Cl)C1=O

InChI Key InChIKey=KKPYTUCEBYOWNU-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29074   

TargetCannabinoid receptor 1(Human)
Pfizer

LigandPNGBDBM29074(ether-based lactam, 19c)
Affinity DataKi:  1.90nM ΔG°:  -12.1kcal/mole EC50:  1.5nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Pfizer

LigandPNGBDBM29074(ether-based lactam, 19c)
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2009
Entry Details Article
PubMed