BDBM291367 4-[2-(6-Aminopyridin-3-yl)-1-(4-chlorophenyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]piperidine-1-carboxamide::US9580415, Example 1

SMILES NC(=O)N1CCC(CC1)c1c(-c2ccc(N)nc2)n(-c2ccc(Cl)cc2)c2cnccc12

InChI Key InChIKey=JMEGFTLLJFBFCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291367   

TargetAmine oxidase [copper-containing] 3(Human)
Proximagen

US Patent
LigandPNGBDBM291367(US9580415, Example 1 | 4-[2-(6-Aminopyridin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in hman et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
US Patent

LigandPNGBDBM291367(US9580415, Example 1 | 4-[2-(6-Aminopyridin-3-yl)-...)
Affinity DataIC50: 5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2019
Entry Details
US Patent