BDBM292036 5-(2-Cyclopentyl-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]pyridin-3-yl)-1,3-dihydro-::US10100045, Example 7

SMILES FC(F)(F)c1ccc2nn(C3CCCC3)c(-c3ccc4[nH]c(=O)[nH]c4c3)c2n1

InChI Key InChIKey=KOMYVVBZMWZJQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292036   

TargetVoltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292036(5-(2-Cyclopentyl-5-(trifluoromethyl)-2H-pyrazolo[4...)
Affinity DataIC50:  15.8nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent