BDBM292173 US10100057, Example 28::US11046702, Example 28::US9745310, Example 28

SMILES COc1cc(c(F)cc1F)-c1cnc2nc(COc3ccccc3)cn2c1

InChI Key InChIKey=XVUBHJRWEAWFNI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292173   

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292173(US10100057, Example 28 | US11046702, Example 28 | ...)
Affinity DataEC50:  750nMT: 25°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292173(US10100057, Example 28 | US11046702, Example 28 | ...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292173(US10100057, Example 28 | US11046702, Example 28 | ...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent