BDBM292382 (S)-N-(2-(diethylamino)propyl)-2-(5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 38

SMILES CCN(CC)[C@@H](C)CNC(=O)c1ccnc(c1)-c1cnn2ccc(nc12)-c1ccccc1

InChI Key InChIKey=JWXMMQUCQWDAIV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292382   

LigandPNGBDBM292382(US10100058, Example 38 | (S)-N-(2-(diethylamino)pr...)
Affinity DataIC50: 2.08nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent

LigandPNGBDBM292382(US10100058, Example 38 | (S)-N-(2-(diethylamino)pr...)
Affinity DataEC50:  29nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent