BDBM292943 US10105367, Example 229::US10376514, Example 229

SMILES COc1ccc(Cn2c3ncc(CN4CCOC(C)C4)cc3c3ncnn3c2=O)cc1

InChI Key InChIKey=AITPEKNDNRONAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292943   

LigandPNGBDBM292943(US10105367, Example 229 | US10376514, Example 229)
Affinity DataIC50: <100nMAssay Description:The selectivity of compounds of the present invention was determined using a panel of recombinant human PDEs and an in vitro enzymatic assay (BPS Bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM292943(US10105367, Example 229 | US10376514, Example 229)
Affinity DataIC50: <100nMT: 25°CAssay Description:PDE1B inhibition was determined by an IMAP TR-FRET assay. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, Calmodulin, cAMP or c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent