BDBM293127 US10106501, Example BJ-19

SMILES CCc1c(N2CCN(C(=O)c3cc4ncncc4[nH]3)CC2)c(=O)n2nc(C3=CCOCC3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=ZJUSJCVXICYMRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293127   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 293127BDBM293127(US20260015358, Example 86)
Affinity DataIC50: 166nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 293127BDBM293127(US20260015358, Example 86)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details US Patent