BDBM29320 BMS-665139::oxazolidin-2-imine, 6c

SMILES [H][C@@]12[C@@H](O)CCN1\C(O[C@H]2C(F)(F)F)=N\c1ccc(C#N)c(Cl)c1C

InChI Key InChIKey=KALFKWQLCWAXJO-RNSKTZJQSA-N

Data  2 KI  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29320   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataKi:  0.300nM ΔG°:  -12.9kcal/mole EC50:  0.200nMpH: 7.6 T: 22°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM29320(BMS-665139 | oxazolidin-2-imine, 6c)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)