BDBM29390 CHEMBL218939::tacrine-dihydropyridine hybrid (tacripyrine), 1
SMILES CCOC(=O)C1C(c2ccccc2)c2c(N)c3CCCCc3nc2N=C1C
InChI Key InChIKey=HSWTUAONRDQBHN-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 29390
Affinity DataIC50: 122nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair