BDBM293979 (2S)-3-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- yl)phenoxy)methyl)benzo[b] thiophen-3-yl)-2-methylpyridine::US10106553, Compound 11

SMILES CC#C[C@@H](Cc1nnn[nH]1)c1ccc(OCc2ccc3scc(-c4cccnc4C)c3c2)cc1

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 293979   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293979((2S)-3-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  88nMT: 25°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293979((2S)-3-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM293979((2S)-3-(5-((4-(1-(1H-Tetrazol-5- yl)pent-3-yn-2- y...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed