BDBM294007 (2S)-5-(2-(4-((2- (Methylsulfonyl)-3-(2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)pent-3- yn-1-yl)-1H-tetrazole::US10106553, Compound 39
SMILES CC#C[C@@H](Cc1nnn[nH]1)c1ccc(OCc2ccc3sc(c(-c4ccccc4C)c3c2)S(C)(=O)=O)cc1
InChI Key
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 294007
Affinity DataEC50: 670nMT: 25°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Affinity DataEC50: 672nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 128nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair