BDBM294014 (2S)-5-(2-(4-((3-(4-(2- Methoxyethoxy)-2- methylphenyl)-2- methylbenzo[b]thiophen-5- yl)methoxy)phenyl)pent-3-yn-1- yl)-1H-tetrazole::US10106553, Compound 46
SMILES COCCOc1ccc(-c2c(C)sc3ccc(COc4ccc(cc4)[C@H](Cc4nnn[nH]4)C#CC)cc23)c(C)c1
InChI Key
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 294014
Affinity DataEC50: 47nMT: 25°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair