BDBM29413 7-alkoxyisoquinoline, 23

SMILES CCS(=O)(=O)N1CCC(CC1)Oc1cc2cnccc2cc1Br

InChI Key InChIKey=RZVRUQLUROIFJM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29413   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Gsk

LigandBDBM29413(7-alkoxyisoquinoline, 23)Copy SMILESCopy InChI

Affinity DataIC50:  5.01E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Gsk

LigandBDBM29413(7-alkoxyisoquinoline, 23)Copy SMILESCopy InChI

Affinity DataIC50: >2.51E+4nMpH: 7.4 T: 22°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL