BDBM29422 7-alkoxyisoquinoline, 32

SMILES NS(=O)(=O)c1ccc(cc1)-c1cc2ccncc2cc1OC1CCCNC1

InChI Key InChIKey=FPCOVWJHQJRSNW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29422   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Gsk

LigandBDBM29422(7-alkoxyisoquinoline, 32)Copy SMILESCopy InChI

Affinity DataIC50:  794nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Gsk

LigandBDBM29422(7-alkoxyisoquinoline, 32)Copy SMILESCopy InChI

Affinity DataIC50:  1.26E+4nMpH: 7.4 T: 22°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL