BDBM29427 7-alkoxyisoquinoline, 37

SMILES CCS(=O)(=O)N1CCC(COc2cc3cnccc3cc2-c2ccccc2)CC1

InChI Key InChIKey=FACNLZWWUQUMDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29427   

LigandPNGBDBM29427(7-alkoxyisoquinoline, 37)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 22°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM29427(7-alkoxyisoquinoline, 37)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM29427(7-alkoxyisoquinoline, 37)
Affinity DataIC50:  2.51E+3nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed