BDBM294493 1-[1-(2,2-difluoroethyl)-2-(2-{4,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}ethyl)-1H-imidazol-4-yl]pyrrolidin-2-one::US9586970, 14

SMILES Cc1cnc(C)c2nc(CCc3nc(cn3CC(F)F)N3CCCC3=O)nn12

InChI Key InChIKey=QRMXLRSOUJRAMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294493   

LigandPNGBDBM294493(US9586970, 14 | 1-[1-(2,2-difluoroethyl)-2-(2-{4,7...)
Affinity DataIC50: 46.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent