BDBM294624 (S)-2-(tert-butoxy)-2-((M)-2-(3,3-dimethylbutanoyl)-6-(8-fluoro-5-methylchroman-6-yl)-4,7-dimethylisoindolin-5-yl)acetic acid::US10112899, Example 104

SMILES Cc1c2CN(Cc2c(C)c(-c2cc(F)c3OCCCc3c2C)c1[C@H](OC(C)(C)C)C(O)=O)C(=O)CC(C)(C)C

InChI Key InChIKey=YDHXCXUNPDZUFI-LJAQVGFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294624   

TargetIntegrase(Human immunodeficiency virus type 1)
Viiv Healthcare

US Patent
LigandPNGBDBM294624((S)-2-(tert-butoxy)-2-((M)-2-(3,3-dimethylbutanoyl...)
Affinity DataIC50:  2nMAssay Description:Antiviral HIV activity and cytotoxicity values for compounds of the invention from Table 1 were measured in parallel in the HTLV-1 transformed cell l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent