BDBM295106 US10112926, Example 35.2::trans-3-(6-Amino-5-(3-(tert-butyl)isoxazol-5-yl)pyridin-3-yl)-N-(−4-hydroxycyclohexyl)-4-methylbenzenesulfonamide hydrochloride

SMILES Cc1ccc(cc1-c1cnc(N)c(c1)-c1cc(no1)C(C)(C)C)S(=O)(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=GLWWXTJSWUKLBH-IYARVYRRSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 295106   

LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50:  270nMpH: 7.5 T: 25°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50:  6.70E+3nMpH: 7.5 T: 25°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50:  90nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPhosphatidylinositol 4-kinase beta(Human)
Novartis

US Patent
LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50:  630nMpH: 7.5 T: 25°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50:  9nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM295106(US10112926, Example 35.2 | trans-3-(6-Amino-5-(3-(...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 25°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent