BDBM295265 6-(2-ethylphenoxy)- 4-(6-methylpyridin-2- ylamino)pyridazine- 3-carboxamide::US10112928, Compound I-7

SMILES CCc1ccccc1Oc1cc(Nc2cccc(C)n2)c(nn1)C(N)=O

InChI Key InChIKey=LIBQVCZGWFNHQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295265   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295265(US10112928, Compound I-7 | 6-(2-ethylphenoxy)- 4-(...)
Affinity DataIC50: 473nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
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