BDBM295269 4-(6-cyclopropyl- pyridin-2-ylamino)-6- oxo-1,6-dihydro- pyridazine-3- carboxylic acid amide::US10112928, Compound I-11

SMILES NC(=O)c1n[nH]c(=O)cc1Nc1cccc(n1)C1CC1

InChI Key InChIKey=DXUQBIOZVASHAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295269   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM295269(US10112928, Compound I-11 | 4-(6-cyclopropyl- pyri...)
Affinity DataIC50: 225nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent